for LigaGuard HCP absorbent technology.
for IgM and IgG on the market today.
TOP SELLING PRODUCTS
LIGAGUARD
LigaTrap’s newly introduced affinity adsorbant, LigaGuard, is a proprietary ensemble of multi-modal ligands which is capable of capturing host cell proteins (HCPs) and DNA selectively in flow-through (continuous) mode. The nature of our resin allows desired bio-products to progress, unbound, with a high purity and recovery.
AAVidity
LigaTrap’s AAVidity is a new affinity resin for serotype-agnostic purification of AAVs from HEK293 and Sf9 lysates. It is functionalized with synthetic affinity ligands that capture AAVs of all serotypes, providing excellent binding capacity and clearance of contaminants (HCPs and hcDNA). High product yield is achieved upon mild elution conditions that safeguard the transduction activity of recovered AAVs.
IgM Resin
LigaTrap’s IgM affinity chromatography purification resins have been proven to be superior in the industry, making the purification of IgM straightforward, affordable and lab efficient. IgM resin has the advantages of extended cycle lives and a milder more basic elution compared to other commonly used resins.
“We have been using LigaTrap mouse IgM purification resin and their custom purification service for two years. The elution buffer is mild, pH3.8, which is a plus for keeping the antibody’s antigen binding ability. In addition, we were very satisfied with the purity and recovery rate of purified IgM from the serum-free hybridoma culture supernatants and their custom purification service.”
The Feinstein Institute for Medical Research
“Searched for affinity chromatography columns/resins to purify antibodies with rat Fc groups, we have found only LigaTrap ratIgG column works. In addition, LT columns can be CIPed with 0.5M NaOH. Purification protocol provided and kind customer service are extra. I strongly recommend LigaTrap ratIgG for rat antibody purification.”
“I am very pleased with the Mouse IgM kit. The sales and technical support teams promptly respond to my queries.”
Purification of mAb Therapeutics by Continuous Chromatography
Presented by
Stefano Menegatti, PhD
Novel Ligands and Modalities for Purifying Gene-editing Products: CRISPR and Viral Vectors
Stefano Menegatti & BioPep Team
Removal of host cell proteins from cell culture fluids by weak partitioning chromatography using peptide-based adsorbents
R. Ashton Lavoie & Group